Cadmium in the structure of L-Chain Horse Apoferritin (pdb 1aew)

The binding sites of Cadmium atom in the structure of L-Chain Horse Apoferritin (pdb code 1aew). This binding sites where shown with 5.0 Angstroms radius around Cadmium atom. The 1aew structure was solved by P.D.HEMPSTEAD, S.J.YEWDALL, D.M.LAWSON, P.M.HARRISON, P.J.ARTYMIUK, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 20.0-1.9 Space group F432 a (A) 184.000 b (A) 184.000 c (A) 184.000 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 19.2 Rfree (%) n/a Cadmium Binding Sites: Cadmium binding site 1 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Asp84, A: Hoh410, A: Hoh2544, conact list: Atom Atom Distance (A) Cd CB A:Asp84 4.23 Cd OD2 A:Asp84 2.11 Cd OD1 A:Asp84 2.73 Cd CG A:Asp84 2.76 Cd O A:Hoh410 1.54 Cd O A:Hoh2544 4.67 interactive model: Cadmium binding site 2 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Asp131, A: Glu134, A: Ser135, conact list: Atom Atom Distance (A) Cd OD1 A:Asp131 3.60 Cd CG A:Asp131 4.83 Cd OE1 A:Glu134 4.82 Cd OG A:Ser135 4.62 interactive model: Cadmium binding site 3 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Asp42, A: Glu49, A: Cys52, A: His53, A: Hoh265, conact list: Atom Atom Distance (A) Cd CB A:Asp42 3.54 Cd OD2 A:Asp42 4.33 Cd OD1 A:Asp42 2.73 Cd CG A:Asp42 3.34 Cd CA A:Asp42 4.21 Cd OE1 A:Glu49 2.51 Cd OE2 A:Glu49 2.50 Cd CD A:Glu49 2.83 Cd CG A:Glu49 4.33 Cd CA A:Glu49 4.94 Cd CB A:Cys52 3.52 Cd SG A:Cys52 2.65 Cd CA A:Cys52 4.97 Cd NE2 A:His53 4.76 Cd CD2 A:His53 4.54 Cd O A:Hoh265 4.31 interactive model: Cadmium binding site 4 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 4 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Cys130, A: Asp131, A: Glu134, A: Cd189, A: Hoh358, conact list: Atom Atom Distance (A) Cd O A:Cys130 4.59 Cd CB A:Cys130 4.56 Cd C A:Cys130 4.42 Cd N A:Asp131 4.23 Cd CB A:Asp131 4.56 Cd OD1 A:Asp131 4.86 Cd CA A:Asp131 4.23 Cd OE1 A:Glu134 2.76 Cd OE2 A:Glu134 3.07 Cd CD A:Glu134 3.22 Cd CG A:Glu134 4.60 Cd CD A:Cd189 4.33 Cd O A:Hoh358 1.67 interactive model: Cadmium binding site 5 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 5 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His118, A: Ser122, A: Cys130, A: Glu134, A: Cd188, A: Hoh358, conact list: Atom Atom Distance (A) Cd NE2 A:His118 2.63 Cd ND1 A:His118 3.90 Cd CD2 A:His118 3.92 Cd CE1 A:His118 2.65 Cd CG A:His118 4.54 Cd OG A:Ser122 3.73 Cd CB A:Cys130 3.54 Cd SG A:Cys130 3.74 Cd CA A:Cys130 4.81 Cd OE2 A:Glu134 3.33 Cd CD A:Glu134 4.57 Cd CD A:Cd188 4.33 Cd O A:Hoh358 3.50 interactive model: Cadmium binding site 6 out of 6 in 1aew Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 6 of Cadmium in the PDB 1aew. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Ser135, A: His136, A: Hoh301, conact list: Atom Atom Distance (A) Cd CB A:Ser135 4.84 Cd NE2 A:His136 2.54 Cd ND1 A:His136 4.57 Cd CD2 A:His136 3.61 Cd CE1 A:His136 3.38 Cd CG A:His136 4.71 Cd O A:Hoh301 4.57 interactive model: