Cadmium in the structure of Crystallographic Studies on A Family Of Cellular Lipophilic Transport Proteins. Refinement Of P2 Myelin Protein And the Structure Determination and Refinement of Cellular Retinol-Binding Protein in Complex With All-Trans-Retinol (pdb 1crb)

The binding sites of Cadmium atom in the structure of Crystallographic Studies on A Family Of Cellular Lipophilic Transport Proteins. Refinement Of P2 Myelin Protein And the Structure Determination and Refinement of Cellular Retinol-Binding Protein in Complex With All-Trans-Retinol (pdb code 1crb). This binding sites where shown with 5.0 Angstroms radius around Cadmium atom. The 1crb structure was solved by S.W.COWAN, T.A.JONES, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 8.0-2.1 Space group P212121 a (A) 40.090 b (A) 47.390 c (A) 69.340 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 18.8 Rfree (%) 24.8 Cadmium Binding Sites: Cadmium binding site 1 out of 2 in 1crb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cadmium in the PDB 1crb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Pro1, A: Asp91, conact list: Atom Atom Distance (A) Cd O A:Pro1 4.27 Cd N A:Pro1 4.34 Cd CB A:Asp91 4.40 Cd OD2 A:Asp91 2.61 Cd OD1 A:Asp91 2.47 Cd CG A:Asp91 2.89 interactive model: Cadmium binding site 2 out of 2 in 1crb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Cadmium in the PDB 1crb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cadmium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Glu118, A: Lys127, A: Hoh349, A: Hoh366, conact list: Atom Atom Distance (A) Cd OE1 A:Glu118 2.59 Cd OE2 A:Glu118 2.79 Cd CD A:Glu118 3.02 Cd CG A:Glu118 4.50 Cd CE A:Lys127 4.12 Cd NZ A:Lys127 4.59 Cd O A:Hoh349 4.11 Cd O A:Hoh366 4.24 interactive model: