Cadmium in PDB 1xmk: The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1

The structure of The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1, PDB code: 1xmk was solved by A.Athanasiadis, D.Placido, S.Maas, B.A.Brown Ii, K.Lowenhaupt, A.Rich, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 0.97
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	35.557, 43.526, 45.471, 90.00, 90.00, 90.00
R / Rfree (%)	14.5 / 18.3

The structure of The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1 also contains other interesting chemical elements:

Nickel	(Ni)	1 atom
Chlorine	(Cl)	2 atoms

The binding sites of Cadmium atom in the The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1 (pdb code 1xmk). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1, PDB code: 1xmk:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in the The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd396 b:10.1 occ:1.00 NZ A:LYS359 2.2 18.5 1.0 CL A:CL399 2.5 13.8 1.0 SG A:CYS304 2.5 9.6 1.0 CE A:LYS359 3.1 18.7 1.0 CB A:CYS304 3.3 9.2 1.0 CD A:CD397 3.7 9.6 1.0 O A:HOH1023 3.9 17.3 1.0 OE2 A:GLU301 4.0 13.2 1.0 O A:HOH1073 4.3 22.7 0.5 CE A:MET363 4.3 14.4 1.0 CD A:LYS359 4.5 16.1 1.0 SD A:MET363 4.6 11.8 1.0 CA A:CYS304 4.7 7.3 1.0

Cadmium binding site 2 out of 2 in the The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of The Crystal Structure of the Zb Domain From the Rna Editing Enzyme ADAR1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd397 b:9.6 occ:1.00 OE1 A:GLU301 2.3 12.5 1.0 OE2 A:GLU301 2.5 13.2 1.0 CL A:CL400 2.5 15.3 1.0 SG A:CYS304 2.6 9.6 1.0 CD A:GLU301 2.8 11.0 1.0 CB A:CYS304 3.7 9.2 1.0 CD A:CD396 3.7 10.1 1.0 CE A:MET363 4.3 14.4 1.0 CG A:GLU301 4.3 11.9 1.0 N A:ASP305 4.5 7.6 0.5 N A:ASP305 4.5 7.3 0.5 C A:CYS304 4.6 6.9 1.0 CA A:CYS304 4.8 7.3 1.0 O A:HOH1023 4.8 17.3 1.0 O A:GLU301 4.9 8.4 1.0 CA A:ASP305 5.0 7.5 0.5 CA A:ASP305 5.0 7.8 0.5

A.Athanasiadis, D.Placido, S.Maas, B.A.Brown Ii, K.Lowenhaupt, A.Rich. The Crystal Structure of the Z[Beta] Domain of the Rna-Editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-Domains. J.Mol.Biol. V. 351 496 2005.
ISSN: ISSN 0022-2836
PubMed: 16023667
DOI: 10.1016/J.JMB.2005.06.028