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Cadmium in PDB 1yhq: Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Protein crystallography data
The structure of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui, PDB code: 1yhq
was solved by
D.Tu,
G.Blaha,
P.B.Moore,
T.A.Steitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.96 / 2.40 |
| Space group | C 2 2 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 212.081, 298.910, 574.815, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 19 / 22.9 |
Other elements in 1yhq:
The structure of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui also contains other interesting chemical elements:
| Strontium | (Sr) | 108 atoms |
| Magnesium | (Mg) | 93 atoms |
| Potassium | (K) | 2 atoms |
| Chlorine | (Cl) | 22 atoms |
| Sodium | (Na) | 75 atoms |
Cadmium Binding Sites:
The binding sites of Cadmium atom in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
(pdb code 1yhq). This binding sites where shown within
5.0 Angstroms radius around Cadmium atom.
In total 5 binding sites of Cadmium where determined in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui, PDB code: 1yhq:
Jump to Cadmium binding site number: 1; 2; 3; 4; 5;
In total 5 binding sites of Cadmium where determined in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui, PDB code: 1yhq:
Jump to Cadmium binding site number: 1; 2; 3; 4; 5;
Cadmium binding site 1 out of 5 in 1yhq
Go back to
Cadmium Binding Sites List in 1yhq
Cadmium binding site 1 out
of 5 in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cadmium with other atoms in the Cd binding
site number 1 of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui within 5.0Å range:
|
Cadmium binding site 2 out of 5 in 1yhq
Go back to
Cadmium Binding Sites List in 1yhq
Cadmium binding site 2 out
of 5 in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cadmium with other atoms in the Cd binding
site number 2 of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui within 5.0Å range:
|
Cadmium binding site 3 out of 5 in 1yhq
Go back to
Cadmium Binding Sites List in 1yhq
Cadmium binding site 3 out
of 5 in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cadmium with other atoms in the Cd binding
site number 3 of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui within 5.0Å range:
|
Cadmium binding site 4 out of 5 in 1yhq
Go back to
Cadmium Binding Sites List in 1yhq
Cadmium binding site 4 out
of 5 in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cadmium with other atoms in the Cd binding
site number 4 of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui within 5.0Å range:
|
Cadmium binding site 5 out of 5 in 1yhq
Go back to
Cadmium Binding Sites List in 1yhq
Cadmium binding site 5 out
of 5 in the Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cadmium with other atoms in the Cd binding
site number 5 of Crystal Structure of Azithromycin Bound to the G2099A Mutant 50S Ribosomal Subunit of Haloarcula Marismortui within 5.0Å range:
|
Reference:
D.Tu,
G.Blaha,
P.B.Moore,
T.A.Steitz.
Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide A Structural Explanation For Resistance. Cell(Cambridge,Mass.) V. 121 257 2005.
ISSN: ISSN 0092-8674
PubMed: 15851032
DOI: 10.1016/J.CELL.2005.02.005
Page generated: Sat Dec 12 08:15:56 2020
ISSN: ISSN 0092-8674
PubMed: 15851032
DOI: 10.1016/J.CELL.2005.02.005
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