Atomistry » Cadmium » PDB 1ykq-2eik » 2a8a
Atomistry »
  Cadmium »
    PDB 1ykq-2eik »
      2a8a »

Cadmium in PDB 2a8a: Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain

Enzymatic activity of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain

All present enzymatic activity of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain:
3.4.24.69;

Protein crystallography data

The structure of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain, PDB code: 2a8a was solved by R.Agarwal, T.Binz, S.Swaminathan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.67 / 2.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 63.413, 79.463, 89.660, 90.00, 110.01, 90.00
R / Rfree (%) 22.6 / 26.5

Other elements in 2a8a:

The structure of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Cadmium Binding Sites:

The binding sites of Cadmium atom in the Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain (pdb code 2a8a). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain, PDB code: 2a8a:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in 2a8a

Go back to Cadmium Binding Sites List in 2a8a
Cadmium binding site 1 out of 2 in the Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cd441

b:16.4
occ:0.50
OD2 A:ASP383 2.3 14.4 1.0
OD1 A:ASP383 2.4 12.3 1.0
CG A:ASP383 2.7 16.6 1.0
O A:HOH605 2.8 2.6 1.0
NZ A:LYS93 3.8 12.8 1.0
CB A:ASP383 4.2 14.6 1.0
CE A:LYS93 4.4 11.5 1.0
O A:HOH592 4.4 19.9 1.0
O A:LEU381 4.9 15.7 1.0
CA A:ASP383 5.0 15.5 1.0

Cadmium binding site 2 out of 2 in 2a8a

Go back to Cadmium Binding Sites List in 2a8a
Cadmium binding site 2 out of 2 in the Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cd442

b:32.5
occ:1.00
O A:HOH494 2.2 17.2 1.0
CD2 A:HIS122 2.5 24.7 1.0
CG A:HIS122 3.2 25.1 1.0
CB A:HIS122 3.4 23.4 1.0
NE2 A:HIS122 3.7 27.4 1.0
CA A:HIS122 4.0 24.1 1.0
ND1 A:HIS122 4.5 25.9 1.0
O A:HIS122 4.7 23.1 1.0
CE1 A:HIS122 4.7 25.9 1.0
C A:HIS122 4.8 23.3 1.0

Reference:

R.Agarwal, T.Binz, S.Swaminathan. Structural Analysis of Botulinum Neurotoxin Serotype F Light Chain: Implications on Substrate Binding and Inhibitor Design Biochemistry V. 44 11758 2005.
ISSN: ISSN 0006-2960
PubMed: 16128577
DOI: 10.1021/BI0510072
Page generated: Wed Oct 28 09:59:02 2020
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy