Cadmium in PDB 2f5h: Solution Structure of the Alpha-Domain of Human Metallothionein-3

The binding sites of Cadmium atom in the Solution Structure of the Alpha-Domain of Human Metallothionein-3 (pdb code 2f5h). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 4 binding sites of Cadmium where determined in the Solution Structure of the Alpha-Domain of Human Metallothionein-3, PDB code: 2f5h:
Jump to Cadmium binding site number: 1; 2; 3; 4;

Cadmium binding site 1 out of 4 in the Solution Structure of the Alpha-Domain of Human Metallothionein-3


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Solution Structure of the Alpha-Domain of Human Metallothionein-3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd69 b:0.1 occ:1.00 SG A:CYS34 2.7 41.2 1.0 SG A:CYS35 2.7 72.1 1.0 SG A:CYS49 2.7 13.2 1.0 SG A:CYS45 2.8 62.5 1.0 HB3 A:CYS45 3.0 1.3 1.0 HA A:CYS49 3.1 23.1 1.0 HB3 A:CYS35 3.3 3.4 1.0 HB2 A:CYS49 3.4 4.3 1.0 O A:CYS34 3.4 23.2 1.0 CB A:CYS45 3.5 13.4 1.0 CB A:CYS49 3.5 74.4 1.0 HB2 A:CYS34 3.6 34.4 1.0 CB A:CYS35 3.6 64.2 1.0 C A:CYS34 3.7 73.2 1.0 CB A:CYS34 3.7 22.2 1.0 CA A:CYS49 3.8 44.4 1.0 H A:CYS34 4.0 12.5 1.0 HB2 A:CYS45 4.0 40.3 1.0 SG A:CYS51 4.1 52.1 1.0 CD A:CD70 4.1 53.2 1.0 CA A:CYS34 4.2 64.5 1.0 N A:CYS35 4.2 4.1 1.0 HB2 A:CYS38 4.3 13.2 1.0 HB2 A:CYS35 4.4 44.5 1.0 N A:CYS34 4.5 2.3 1.0 HB3 A:CYS49 4.5 15.1 1.0 CA A:CYS35 4.6 61.4 1.0 HB2 A:CYS51 4.6 22.1 1.0 H A:VAL50 4.6 34.3 1.0 HA A:CYS45 4.7 42.4 1.0 HB3 A:CYS34 4.7 22.1 1.0 CA A:CYS45 4.7 43.2 1.0 C A:CYS49 4.8 50.2 1.0 H A:CYS35 4.8 34.3 1.0 N A:CYS49 4.8 31.4 1.0

Cadmium binding site 2 out of 4 in the Solution Structure of the Alpha-Domain of Human Metallothionein-3


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Solution Structure of the Alpha-Domain of Human Metallothionein-3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd70 b:53.2 occ:1.00 SG A:CYS37 2.7 32.1 1.0 SG A:CYS51 2.7 52.1 1.0 SG A:CYS38 2.8 14.0 1.0 SG A:CYS35 2.8 72.1 1.0 HB2 A:CYS38 3.0 13.2 1.0 HB2 A:CYS35 3.1 44.5 1.0 CB A:CYS38 3.4 14.4 1.0 CB A:CYS35 3.5 64.2 1.0 H A:CYS37 3.5 11.2 1.0 HB3 A:CYS51 3.7 71.3 1.0 HB3 A:CYS35 3.7 3.4 1.0 HB2 A:CYS37 3.7 65.1 1.0 CB A:CYS51 3.7 5.5 1.0 CB A:CYS37 3.7 23.2 1.0 N A:CYS38 3.7 31.4 1.0 H A:CYS38 3.8 55.4 1.0 C A:CYS37 3.8 44.3 1.0 HB2 A:CYS51 3.9 22.1 1.0 SG A:CYS64 4.0 65.4 1.0 CD A:CD72 4.0 33.4 1.0 CD A:CD69 4.1 0.1 1.0 CA A:CYS37 4.1 52.4 1.0 N A:CYS37 4.2 35.5 1.0 CD A:CD71 4.2 43.2 1.0 CA A:CYS38 4.2 73.0 1.0 O A:CYS37 4.3 24.3 1.0 HB3 A:CYS38 4.3 11.1 1.0 SG A:CYS45 4.3 62.5 1.0 HB3 A:CYS64 4.6 51.5 1.0 H A:SER36 4.7 1.1 1.0 HB3 A:CYS37 4.7 3.3 1.0 HA A:CYS38 4.9 13.4 1.0 CA A:CYS35 4.9 61.4 1.0 CB A:CYS64 5.0 0.2 1.0

Cadmium binding site 3 out of 4 in the Solution Structure of the Alpha-Domain of Human Metallothionein-3


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of Solution Structure of the Alpha-Domain of Human Metallothionein-3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd71 b:43.2 occ:1.00 SG A:CYS45 2.8 62.5 1.0 SG A:CYS42 2.8 54.1 1.0 SG A:CYS38 2.8 14.0 1.0 SG A:CYS67 2.8 4.2 1.0 HB3 A:CYS38 3.2 11.1 1.0 HB3 A:CYS67 3.3 51.5 1.0 HB2 A:LYS44 3.3 43.3 1.0 HB2 A:CYS67 3.4 44.3 1.0 CB A:CYS67 3.4 51.3 1.0 HB2 A:CYS45 3.4 40.3 1.0 CB A:CYS38 3.5 14.4 1.0 HB2 A:CYS38 3.6 13.2 1.0 H A:CYS45 3.6 40.4 1.0 HB3 A:CYS42 3.6 75.2 1.0 CB A:CYS45 3.7 13.4 1.0 CB A:CYS42 3.8 73.5 1.0 CD A:CD72 3.9 33.4 1.0 HB2 A:CYS42 3.9 23.2 1.0 HB3 A:LYS44 4.0 0.4 1.0 N A:CYS45 4.0 43.5 1.0 CB A:LYS44 4.1 3.3 1.0 SG A:CYS51 4.2 52.1 1.0 CD A:CD70 4.2 53.2 1.0 HG21 A:VAL50 4.4 0.5 1.0 CA A:CYS45 4.5 43.2 1.0 HB3 A:CYS45 4.6 1.3 1.0 C A:LYS44 4.7 1.3 1.0 HD2 A:PRO39 4.7 1.0 1.0 H A:LYS44 4.7 61.2 1.0 HA A:CYS45 4.8 42.4 1.0 CA A:LYS44 4.9 71.1 1.0 SG A:CYS64 4.9 65.4 1.0 CA A:CYS67 4.9 14.6 1.0 CA A:CYS38 5.0 73.0 1.0 HG23 A:VAL50 5.0 70.0 1.0

Cadmium binding site 4 out of 4 in the Solution Structure of the Alpha-Domain of Human Metallothionein-3


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 4 of Solution Structure of the Alpha-Domain of Human Metallothionein-3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd72 b:33.4 occ:1.00 SG A:CYS66 2.7 63.1 1.0 SG A:CYS51 2.7 52.1 1.0 SG A:CYS67 2.8 4.2 1.0 SG A:CYS64 2.9 65.4 1.0 HB2 A:CYS67 2.9 44.3 1.0 HB2 A:CYS64 2.9 1.2 1.0 H A:CYS67 3.2 44.5 1.0 CB A:CYS67 3.4 51.3 1.0 CB A:CYS64 3.4 0.2 1.0 HB2 A:CYS66 3.6 14.1 1.0 HA A:CYS51 3.6 14.2 1.0 N A:CYS67 3.6 71.0 1.0 HB3 A:CYS51 3.6 71.3 1.0 CB A:CYS51 3.7 5.5 1.0 CB A:CYS66 3.8 20.3 1.0 HB3 A:CYS64 3.8 51.5 1.0 HG21 A:VAL50 3.8 0.5 1.0 CD A:CD71 3.9 43.2 1.0 CD A:CD70 4.0 53.2 1.0 O A:VAL50 4.0 30.0 1.0 SG A:CYS38 4.1 14.0 1.0 CA A:CYS51 4.1 24.0 1.0 CA A:CYS67 4.1 14.6 1.0 C A:CYS66 4.2 52.1 1.0 HB3 A:CYS67 4.3 51.5 1.0 CA A:CYS66 4.4 32.1 1.0 C A:VAL50 4.5 64.2 1.0 N A:CYS51 4.5 73.4 1.0 H A:CYS66 4.6 1.3 1.0 HG22 A:VAL50 4.6 11.3 1.0 HB3 A:CYS66 4.6 35.0 1.0 N A:CYS66 4.6 74.3 1.0 HB2 A:CYS51 4.7 22.1 1.0 CG2 A:VAL50 4.7 2.1 1.0 CA A:CYS64 4.8 42.1 1.0 HA A:CYS67 4.9 41.5 1.0 C A:CYS64 5.0 64.5 1.0

H.Wang, Q.Zhang, B.Cai, H.Y.Li, K.H.Sze, Z.X.Huang, H.M.Wu, H.Z.Sun. Solution Structure and Dynamics of Human Metallothionein-3 (Mt-3) Febs Lett. V. 580 795 2006.
ISSN: ISSN 0014-5793
PubMed: 16413543
DOI: 10.1016/J.FEBSLET.2005.12.099