Cadmium in PDB 2x28: Cadmium Bound Structure of Sporosag

The structure of Cadmium Bound Structure of Sporosag, PDB code: 2x28 was solved by J.Crawford, E.Lamb, J.Wasmuth, O.Grujic, M.E.Grigg, M.J.Boulanger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.27 / 2.15
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	102.620, 72.970, 30.660, 90.00, 90.00, 90.00
R / Rfree (%)	23.564 / 28.936

The binding sites of Cadmium atom in the Cadmium Bound Structure of Sporosag (pdb code 2x28). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 5 binding sites of Cadmium where determined in the Cadmium Bound Structure of Sporosag, PDB code: 2x28:
Jump to Cadmium binding site number: 1; 2; 3; 4; 5;

Cadmium binding site 1 out of 5 in the Cadmium Bound Structure of Sporosag


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Cadmium Bound Structure of Sporosag within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1239 b:46.5 occ:1.00 OE2 A:GLU144 2.4 27.5 1.0 OE1 A:GLU144 2.7 24.9 1.0 CD A:GLU144 2.9 22.7 1.0 CG A:GLU144 4.3 17.6 1.0 CB A:GLU144 4.9 15.9 1.0

Cadmium binding site 2 out of 5 in the Cadmium Bound Structure of Sporosag


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Cadmium Bound Structure of Sporosag within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1240 b:35.9 occ:1.00 O A:HOH2059 2.3 7.4 1.0 OD1 A:ASP87 2.6 13.9 1.0 OD2 A:ASP87 2.7 16.7 1.0 CG A:ASP87 3.0 13.2 1.0 O A:HOH2056 3.0 16.3 1.0 OG A:SER67 4.3 12.7 1.0 O A:HOH2070 4.4 27.9 1.0 O A:SER65 4.4 17.6 1.0 CB A:ASP87 4.5 16.1 1.0 CG2 A:THR85 4.6 17.4 1.0 CB A:THR85 4.8 16.3 1.0 O A:HOH2057 4.9 26.4 1.0 CB A:SER67 4.9 14.8 1.0

Cadmium binding site 3 out of 5 in the Cadmium Bound Structure of Sporosag


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of Cadmium Bound Structure of Sporosag within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1241 b:35.4 occ:1.00 OE2 A:GLU18 2.2 25.5 1.0 ND1 A:HIS22 2.4 24.0 1.0 CD A:GLU18 3.2 28.4 1.0 CE1 A:HIS22 3.3 24.0 1.0 CG A:HIS22 3.4 22.1 1.0 CB A:HIS22 3.6 20.8 1.0 CG A:GLU18 3.8 24.8 1.0 OE1 A:GLU18 4.2 33.8 1.0 NE2 A:HIS22 4.5 27.3 1.0 O A:THR16 4.5 13.3 1.0 CD2 A:HIS22 4.5 22.9 1.0 O A:VAL23 4.8 19.1 1.0 N A:GLU18 4.9 16.6 1.0 CA A:HIS22 5.0 19.5 1.0

Cadmium binding site 4 out of 5 in the Cadmium Bound Structure of Sporosag


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 4 of Cadmium Bound Structure of Sporosag within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1242 b:23.0 occ:1.00 ND1 A:HIS124 2.4 11.5 1.0 OG A:SER14 2.9 19.6 1.0 CB A:SER14 3.2 19.7 1.0 CE1 A:HIS124 3.3 13.7 1.0 CG A:HIS124 3.5 14.7 1.0 CB A:HIS124 3.8 14.9 1.0 O A:HOH2010 3.9 26.1 1.0 NE2 A:HIS124 4.5 15.7 1.0 CD2 A:HIS124 4.6 14.6 1.0 CA A:SER14 4.7 18.6 1.0 O A:HIS124 4.9 12.5 1.0

Cadmium binding site 5 out of 5 in the Cadmium Bound Structure of Sporosag


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 5 of Cadmium Bound Structure of Sporosag within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1243 b:47.1 occ:1.00 NE2 A:HIS191 2.2 20.3 1.0 O A:HOH2153 3.0 16.5 1.0 CD2 A:HIS191 3.1 18.3 1.0 CE1 A:HIS191 3.3 22.0 1.0 CG A:HIS191 4.3 21.1 1.0 ND1 A:HIS191 4.3 21.6 1.0 OD2 A:ASP209 4.6 24.4 1.0 O A:HOH2066 4.7 14.5 1.0

J.Crawford, E.Lamb, J.Wasmuth, O.Grujic, M.E.Grigg, M.J.Boulanger. Structural and Functional Characterization of Sporosag: A SAG2 Related Surface Antigen From Toxoplasma Gondii. J.Biol.Chem. V. 285 12063 2010.
ISSN: ISSN 0021-9258
PubMed: 20164173
DOI: 10.1074/JBC.M109.054866