Cadmium in PDB 2z4q: Crystal Structure of A Murine Antibody Fab 528

The structure of Crystal Structure of A Murine Antibody Fab 528, PDB code: 2z4q was solved by T.Nakanishi, K.Tsumoto, R.Asano, H.Kondo, I.Kumagai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.95 / 2.30
Space group	P 62
Cell size a, b, c (Å), α, β, γ (°)	126.600, 126.600, 68.278, 90.00, 90.00, 120.00
R / Rfree (%)	19.1 / 22.8

The structure of Crystal Structure of A Murine Antibody Fab 528 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Cadmium atom in the Crystal Structure of A Murine Antibody Fab 528 (pdb code 2z4q). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Crystal Structure of A Murine Antibody Fab 528, PDB code: 2z4q:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in the Crystal Structure of A Murine Antibody Fab 528


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of A Murine Antibody Fab 528 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd1002 b:60.3 occ:0.60 OE1 A:GLU190 2.7 43.7 1.0 NE2 A:HIS194 2.7 25.1 1.0 OE2 A:GLU190 3.1 42.1 1.0 CD A:GLU190 3.3 40.3 1.0 CE1 A:HIS194 3.7 25.8 1.0 CD2 A:HIS194 3.7 25.0 1.0 CD A:ARG193 4.0 39.3 1.0 NH1 A:ARG193 4.3 44.3 1.0 CG A:ARG193 4.6 35.6 1.0 CG A:GLU190 4.7 38.1 1.0 CB A:ARG193 4.8 28.2 1.0 ND1 A:HIS194 4.8 26.4 1.0 CG A:HIS194 4.8 26.4 1.0

Cadmium binding site 2 out of 2 in the Crystal Structure of A Murine Antibody Fab 528


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Crystal Structure of A Murine Antibody Fab 528 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cd1001 b:23.1 occ:1.00 ND1 B:HIS41 2.3 21.2 1.0 NE2 B:HIS43 2.3 23.8 1.0 CE1 B:HIS41 3.0 22.9 1.0 CE1 B:HIS43 3.1 24.3 1.0 CG B:HIS41 3.4 22.9 1.0 CD2 B:HIS43 3.5 22.5 1.0 CB B:HIS41 3.9 21.0 1.0 NE2 B:HIS41 4.2 20.2 1.0 ND1 B:HIS43 4.3 26.8 1.0 CD2 B:HIS41 4.4 21.3 1.0 CG B:HIS43 4.5 24.7 1.0 NE B:ARG40 4.9 46.7 1.0

K.Makabe, T.Nakanishi, K.Tsumoto, Y.Tanaka, H.Kondo, M.Umetsu, Y.Sone, R.Asano, I.Kumagai. Thermodynamic Consequences of Mutations in Vernier Zone Residues of A Humanized Anti-Human Epidermal Growth Factor Receptor Murine Antibody, 528 J.Biol.Chem. V. 283 1156 2008.
ISSN: ISSN 0021-9258
PubMed: 17947238
DOI: 10.1074/JBC.M706190200