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Atomistry » Cadmium » PDB 3cn6-3haf » 3eig » |
Cadmium in PDB 3eig: Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate ReductaseEnzymatic activity of Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase
All present enzymatic activity of Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase:
1.5.1.3; Protein crystallography data
The structure of Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase, PDB code: 3eig
was solved by
B.J.Yachnin,
A.M.Berghuis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Cadmium Binding Sites:
The binding sites of Cadmium atom in the Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase
(pdb code 3eig). This binding sites where shown within
5.0 Angstroms radius around Cadmium atom.
In total only one binding site of Cadmium was determined in the Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase, PDB code: 3eig: Cadmium binding site 1 out of 1 in 3eigGo back to Cadmium Binding Sites List in 3eig
Cadmium binding site 1 out
of 1 in the Crystal Structure of A Methotrexate-Resistant Mutant of Human Dihydrofolate Reductase
Mono view Stereo pair view
Reference:
J.P.Volpato,
B.J.Yachnin,
J.Blanchet,
V.Guerrero,
L.Poulin,
E.Fossati,
A.M.Berghuis,
J.N.Pelletier.
Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis For Methotrexate Resistance. J.Biol.Chem. V. 284 20079 2009.
Page generated: Fri Jul 19 15:52:03 2024
ISSN: ISSN 0021-9258 PubMed: 19478082 DOI: 10.1074/JBC.M109.018010 |
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