Cadmium in PDB 3wa4: GRB2 SH2 Domain/CD28-Derived Peptide Complex

The structure of GRB2 SH2 Domain/CD28-Derived Peptide Complex, PDB code: 3wa4 was solved by K.Higo, M.Oda, N.Ito, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.54 / 1.35
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	59.010, 59.010, 117.090, 90.00, 90.00, 120.00
R / Rfree (%)	17.6 / 20.9

The binding sites of Cadmium atom in the GRB2 SH2 Domain/CD28-Derived Peptide Complex (pdb code 3wa4). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total only one binding site of Cadmium was determined in the GRB2 SH2 Domain/CD28-Derived Peptide Complex, PDB code: 3wa4:

Cadmium binding site 1 out of 1 in the GRB2 SH2 Domain/CD28-Derived Peptide Complex


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of GRB2 SH2 Domain/CD28-Derived Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd201 b:15.9 occ:1.00 NE2 A:HIS79 2.3 14.0 1.0 O A:ACY202 2.3 21.0 1.0 OXT A:ACY202 2.4 19.6 1.0 OE1 A:GLU152 2.5 31.4 1.0 OE2 A:GLU152 2.6 26.9 1.0 C A:ACY202 2.7 15.9 1.0 CD A:GLU152 2.9 20.4 1.0 CD2 A:HIS79 3.2 14.2 1.0 CE1 A:HIS79 3.3 16.7 1.0 NH2 A:ARG149 4.2 14.8 1.0 CH3 A:ACY202 4.3 20.1 1.0 ND1 A:HIS79 4.4 15.5 1.0 CG A:HIS79 4.4 13.3 1.0 CG A:GLU152 4.4 19.9 1.0 NE A:ARG78 4.8 26.7 1.0 NH2 A:ARG78 4.9 27.3 1.0

K.Higo, T.Ikura, M.Oda, H.Morii, J.Takahashi, R.Abe, N.Ito. High Resolution Crystal Structure of the GRB2 SH2 Domain with A Phosphopeptide Derived From CD28 Plos One V. 8 74482 2013.
ISSN: ESSN 1932-6203
PubMed: 24098653
DOI: 10.1371/JOURNAL.PONE.0074482