Cadmium in PDB 4lny: Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422

The structure of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422, PDB code: 4lny was solved by S.Vorobiev, M.Su, S.Bjelic, Y.Kipnis, L.Wang, S.Sahdev, R.Xiao, M.Maglaqui, S.Kogan, D.Baker, J.K.Everett, T.B.Acton, G.T.Montelione, J.F.Hunt, L.Tong, Northeast Structural Genomics Consortium (Nesg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.14 / 1.93
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.125, 63.161, 86.436, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 22.2

The structure of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 also contains other interesting chemical elements:

Chlorine

(Cl)

5 atoms

The binding sites of Cadmium atom in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 (pdb code 4lny). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 6 binding sites of Cadmium where determined in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422, PDB code: 4lny:
Jump to Cadmium binding site number: 1; 2; 3; 4; 5; 6;

Cadmium binding site 1 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd301 b:28.8 occ:1.00 OE2 A:GLU218 2.4 32.0 1.0 OE1 A:GLU218 2.5 24.3 1.0 O A:HOH531 2.5 28.0 1.0 CL A:CL307 2.5 24.4 1.0 CD A:GLU218 2.8 26.4 1.0 CB A:SER214 3.0 28.4 1.0 OG A:SER214 3.1 44.9 1.0 N A:SER214 3.7 24.2 1.0 NZ A:LYS191 3.7 35.0 1.0 CA A:SER214 3.9 30.7 1.0 O A:HOH626 4.0 58.1 1.0 CG A:GLU218 4.3 23.4 1.0 CG A:GLU215 4.4 43.8 1.0 C A:ILE213 4.5 23.6 1.0 N A:GLU215 4.6 25.1 1.0 C A:SER214 4.6 31.5 1.0 OE2 A:GLU215 4.7 47.6 1.0 CE A:LYS191 4.7 32.7 1.0 O A:HOH526 4.8 42.2 1.0 CA A:ILE213 4.9 17.1 1.0

Cadmium binding site 2 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd302 b:51.0 occ:1.00 OE1 A:GLU68 2.5 42.9 1.0 OE2 A:GLU68 2.8 50.7 1.0 CD A:GLU68 3.0 44.7 1.0 O A:HOH561 4.0 35.4 1.0 CG A:GLU68 4.5 41.9 1.0

Cadmium binding site 3 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd303 b:55.7 occ:1.00 O A:HOH595 2.4 34.9 1.0 OD2 A:ASP183 2.6 41.9 1.0 OD1 A:ASP183 2.7 37.0 1.0 CL A:CL309 2.7 53.8 1.0 CG A:ASP183 3.0 40.2 1.0 O A:HOH554 3.1 39.5 1.0 OE1 A:GLU185 3.1 78.0 1.0 CD A:GLU185 4.0 74.8 1.0 CB A:GLU185 4.1 60.9 1.0 N A:GLU185 4.2 44.4 1.0 O A:HOH593 4.4 43.8 1.0 CB A:ASP183 4.4 35.9 1.0 CG A:GLU185 4.4 67.8 1.0 NZ A:LYS135 4.5 43.6 1.0 N A:TRP184 4.7 36.0 1.0 CA A:GLU185 4.8 52.1 1.0 OE2 A:GLU185 4.8 76.5 1.0 CE A:LYS135 4.9 41.4 1.0

Cadmium binding site 4 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 4 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd304 b:96.0 occ:1.00 OD2 A:ASP65 2.6 49.5 1.0 OD1 A:ASP65 2.7 36.4 1.0 CG A:ASP65 3.0 38.4 1.0 CG1 A:ILE67 4.0 39.6 1.0 CB A:ILE67 4.0 33.3 1.0 CB A:ASP65 4.4 33.1 1.0 N A:ILE67 4.6 25.5 1.0 O A:HOH628 4.7 73.7 1.0 CD A:PRO66 4.8 28.3 1.0 CA A:ILE67 4.9 29.1 1.0 O A:HOH614 4.9 46.6 1.0

Cadmium binding site 5 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 5 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd305 b:74.7 occ:1.00 OD2 A:ASP162 2.6 44.0 1.0 O A:HOH612 2.7 55.9 1.0 OD1 A:ASP165 2.9 29.7 1.0 OD1 A:ASP162 3.3 37.0 1.0 CG A:ASP162 3.4 39.2 1.0 CG A:ASP165 3.6 29.8 1.0 OD2 A:ASP165 3.6 32.3 1.0 CB A:ASP162 4.8 31.5 1.0 CB A:ASP165 4.8 27.2 1.0 N A:ASP165 4.8 28.6 1.0 ND2 A:ASN164 4.9 45.4 1.0 CB A:ASN164 5.0 35.4 1.0

Cadmium binding site 6 out of 6 in the Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 6 of Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd306 b:0.7 occ:1.00 OE1 A:GLU147 2.7 35.7 1.0 OE2 A:GLU147 3.0 48.9 1.0 CD A:GLU147 3.2 37.1 1.0 CG A:GLU147 4.7 31.1 1.0

S.Vorobiev, M.Su, S.Bjelic, Y.Kipnis, L.Wang, S.Sahdev, R.Xiao, M.Maglaqui, S.Kogan, D.Baker, J.K.Everett, T.B.Acton, G.T.Montelione, J.F.Hunt, L.Tong. Crystal Structure of Engineered Protein OR422. To Be Published.