Cadmium in PDB 5zi8: Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion

The structure of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion, PDB code: 5zi8 was solved by K.Meera, R.K.Pal, A.Arora, B.K.Biswal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	63.67 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	30.496, 49.291, 127.338, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 24

The binding sites of Cadmium atom in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion (pdb code 5zi8). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion, PDB code: 5zi8:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd201 b:43.9 occ:1.00 OE2 A:GLU30 2.2 35.2 1.0 O A:HOH323 2.3 42.5 1.0 NE2 A:HIS16 2.3 37.9 1.0 NE2 A:HIS34 2.5 33.2 1.0 O A:HOH332 2.7 36.0 1.0 O A:HOH325 2.9 36.4 1.0 CE1 A:HIS16 3.2 36.3 1.0 CD A:GLU30 3.2 33.6 1.0 CD2 A:HIS34 3.4 34.6 1.0 CD2 A:HIS16 3.4 35.8 1.0 CE1 A:HIS34 3.5 35.6 1.0 CG A:GLU30 3.7 31.4 1.0 O A:HOH304 3.8 44.6 1.0 OE1 A:GLU30 4.3 32.3 1.0 ND1 A:HIS16 4.4 36.7 1.0 CG A:HIS16 4.5 35.8 1.0 CG A:HIS34 4.5 35.1 1.0 ND1 A:HIS34 4.6 36.6 1.0

Cadmium binding site 2 out of 2 in the Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Crystal Structure of the Padr-Family Transcriptional Regulator RV3488 of Mycobacterium Tuberculosis H37RV in Complex with Cadmium Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd202 b:34.3 occ:1.00 OE2 B:GLU30 2.2 28.7 1.0 NE2 B:HIS16 2.3 30.1 1.0 NE2 A:HIS101 2.3 50.1 1.0 NE2 B:HIS34 2.4 28.7 1.0 O B:HOH320 2.4 28.5 1.0 O A:HOH313 2.9 32.5 1.0 CE1 A:HIS101 3.1 50.4 1.0 CE1 B:HIS16 3.2 28.8 1.0 CD2 B:HIS34 3.3 29.1 1.0 CD B:GLU30 3.3 29.5 1.0 CE1 B:HIS34 3.4 30.2 1.0 CD2 B:HIS16 3.4 26.9 1.0 CD2 A:HIS101 3.4 52.3 1.0 CG B:GLU30 3.7 29.6 1.0 OE1 B:GLU30 4.3 28.6 1.0 ND1 B:HIS16 4.3 27.5 1.0 ND1 A:HIS101 4.3 55.2 1.0 CG B:HIS34 4.4 29.3 1.0 CG B:HIS16 4.5 26.8 1.0 ND1 B:HIS34 4.5 30.5 1.0 CG A:HIS101 4.5 55.5 1.0

M.Kumari, R.K.Pal, A.K.Mishra, S.Tripathi, B.K.Biswal, K.K.Srivastava, A.Arora. Structural and Functional Characterization of the Transcriptional Regulator RV3488 Ofmycobacterium TUBERCULOSISH37RV. Biochem. J. V. 475 3393 2018.
ISSN: ESSN 1470-8728
PubMed: 30266832
DOI: 10.1042/BCJ20180356