Cadmium in PDB 6ppg: Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A

The structure of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A, PDB code: 6ppg was solved by C.S.Huang, J.P.Yin, S.G.Hymowitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.79 / 2.75
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.820, 103.820, 243.327, 90.00, 90.00, 120.00
R / Rfree (%)	22.4 / 27.5

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 53;

Binding sites:

The binding sites of Cadmium atom in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A (pdb code 6ppg). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 53 binding sites of Cadmium where determined in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A, PDB code: 6ppg:
Jump to Cadmium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Cadmium binding site 1 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ F:Cd202 b:54.0 occ:1.00 OE1 F:GLU45 2.1 56.5 1.0 OE2 F:GLU45 2.1 51.5 1.0 O F:MET40 2.2 64.8 1.0 O F:HOH306 2.2 11.1 1.0 CD F:GLU45 2.4 51.4 1.0 O F:HOH307 2.4 20.6 1.0 O F:HOH310 2.5 15.2 1.0 C F:MET40 3.2 62.7 1.0 CG F:GLU45 3.9 48.3 1.0 CA F:MET40 4.0 62.9 1.0 N F:ASN43 4.1 50.8 1.0 N F:SER41 4.2 60.9 1.0 CB F:MET40 4.2 63.9 1.0 CA F:ASN43 4.3 51.2 1.0 CE2 F:TYR54 4.6 33.1 1.0 N F:ARG42 4.6 54.2 1.0 CA F:SER41 4.6 59.3 1.0 OH F:TYR54 4.6 31.3 1.0 N F:ILE44 4.7 48.2 1.0 CB F:GLU45 4.8 47.9 1.0 C F:SER41 4.9 54.9 1.0 C F:ASN43 5.0 49.8 1.0

Cadmium binding site 2 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ F:Cd203 b:48.7 occ:1.00 OE1 F:GLU66 2.1 49.3 1.0 OE2 F:GLU66 2.1 47.4 1.0 CD F:GLU66 2.4 46.4 1.0 O F:HOH308 2.4 22.8 1.0 O F:HOH309 2.5 11.2 1.0 O F:HOH317 2.8 31.2 1.0 CG F:GLU66 3.8 45.1 1.0 CB F:GLU66 4.7 44.9 1.0

Cadmium binding site 3 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ F:Cd204 b:74.4 occ:1.00 OE2 F:GLU34 2.1 79.9 1.0 OE1 F:GLU34 2.1 76.1 1.0 CD F:GLU34 2.4 75.7 1.0 O F:HOH311 3.1 34.4 1.0 CG F:GLU34 3.9 70.4 1.0 O F:HOH302 3.9 51.3 1.0 OH F:TYR63 4.8 57.0 1.0 CB F:GLU34 4.8 68.7 1.0

Cadmium binding site 4 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 4 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ F:Cd205 b:0.0 occ:1.00 O F:HOH316 3.5 56.8 1.0 CB F:HIS104 3.8 94.7 1.0 CA F:HIS104 4.1 95.3 1.0 OG F:SER108 4.5 0.9 1.0 N F:GLN105 4.6 0.6 1.0 C F:HIS104 4.9 99.3 1.0

Cadmium binding site 5 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 5 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ F:Cd206 b:0.7 occ:1.00 O F:ILE129 2.2 96.1 1.0 C F:ILE129 3.3 69.7 1.0 O H:HOH409 3.3 33.9 1.0 O H:ILE100 3.9 51.7 1.0 CA F:ILE129 4.1 64.7 1.0 CA H:GLY102 4.1 48.7 1.0 N H:GLY102 4.2 51.2 1.0 C H:GLY101 4.6 51.3 1.0 OH H:TYR32 4.6 40.7 1.0 O H:GLY101 4.6 52.2 1.0 CG2 F:ILE129 4.7 65.7 1.0 C H:ILE100 4.9 50.2 1.0

Cadmium binding site 6 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 6 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd301 b:78.8 occ:0.50 O A:HOH426 2.3 44.7 0.5 OE2 A:GLU124 3.6 0.6 1.0 CD A:CD304 3.8 0.8 1.0 CD A:GLU124 3.9 97.1 1.0 CB A:ASP123 4.1 92.7 1.0 OE1 A:GLU124 4.3 0.5 1.0 CG A:GLU124 4.4 86.7 1.0 OD2 A:ASP123 4.4 0.7 1.0 CG A:ASP123 4.7 0.4 1.0 N A:GLU124 4.9 79.2 1.0

Cadmium binding site 7 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 7 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd302 b:71.1 occ:1.00 OE2 A:GLU81 2.2 64.9 1.0 OE1 A:GLU81 2.2 65.4 1.0 CD A:GLU81 2.5 62.2 1.0 O A:HOH414 2.7 38.3 1.0 CG A:GLU81 4.0 57.6 1.0 NH2 A:ARG45 4.4 59.5 1.0 NZ A:LYS39 4.6 57.1 1.0 NH1 A:ARG45 4.6 61.6 1.0 NH2 A:ARG61 4.9 37.3 1.0 CZ A:ARG45 4.9 60.4 1.0 CB A:GLU81 4.9 52.8 1.0

Cadmium binding site 8 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 8 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd303 b:0.5 occ:1.00 OD2 A:ASP168 2.2 0.2 1.0 OD1 A:ASP168 2.2 0.8 1.0 CG A:ASP168 2.5 92.0 1.0 CB A:ASP168 4.0 80.0 1.0 CB A:LYS170 4.5 60.2 1.0 CE1 B:HIS174 4.6 60.6 1.0 O B:HOH401 4.6 27.4 1.0 CD A:CD306 4.7 97.0 1.0 CA A:ASP168 4.7 69.0 1.0 N A:LYS170 4.8 64.5 1.0 OD2 A:ASP171 4.8 65.0 1.0 N A:SER169 4.9 68.9 1.0

Cadmium binding site 9 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 9 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd304 b:0.8 occ:1.00 OE1 A:GLU124 2.2 0.5 1.0 OE2 A:GLU124 2.2 0.6 1.0 CD A:GLU124 2.5 97.1 1.0 O A:HOH420 3.7 33.2 1.0 CD A:CD301 3.8 78.8 0.5 CG A:GLU124 4.0 86.7 1.0 N A:ASP123 4.0 75.7 1.0 CB A:ASP123 4.1 92.7 1.0 CG A:ASP123 4.3 0.4 1.0 N A:GLU124 4.4 79.2 1.0 OD2 A:ASP123 4.4 0.7 1.0 CB A:SER122 4.5 62.0 1.0 CA A:ASP123 4.6 83.4 1.0 O A:HOH426 4.7 44.7 0.5 CG B:PRO133 4.8 47.3 1.0 CB A:GLU124 4.9 81.3 1.0 OD1 A:ASP123 4.9 0.9 1.0 CA A:SER122 4.9 62.9 1.0 C A:SER122 4.9 69.8 1.0 C A:ASP123 5.0 81.9 1.0

Cadmium binding site 10 out of 53 in the Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 10 of Crystal Structure of IL17FF Bound to Fab Fragments of MCAF5352A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd305 b:0.9 occ:1.00 O A:ASN211 3.2 61.8 1.0 O A:HOH423 3.2 54.3 1.0 C A:ASN211 4.3 62.5 1.0 CD A:CD316 4.4 0.8 0.5 CB A:ASN211 4.5 64.3 1.0 N A:ASN211 4.6 63.2 1.0 CA A:ASN211 4.7 63.8 1.0

C.Tilegenova, S.Izadi, J.Yin, C.S.Huang, J.Wu, D.Ellerman, S.G.Hymowitz, B.Walters, C.Salisbury, P.J.Carter. Dissecting the Molecular Basis of High Viscosity of Monospecific and Bispecific Igg Antibodies. Mabs V. 12 92764.
ISSN: ESSN 1942-0870
PubMed: 31779513
DOI: 10.1080/19420862.2019.1692764