Atomistry » Cadmium » PDB 7jod-7viq » 7utw
Atomistry »
  Cadmium »
    PDB 7jod-7viq »
      7utw »

Cadmium in PDB 7utw: Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide

Enzymatic activity of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide

All present enzymatic activity of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide:
1.1.1.1;

Protein crystallography data

The structure of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide, PDB code: 7utw was solved by C.Zheng, S.G.Boxer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.02 / 1.33
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 44.206, 50.807, 92.903, 92.39, 102.93, 109.33
R / Rfree (%) 13.8 / 16.5

Other elements in 7utw:

The structure of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Cadmium Binding Sites:

The binding sites of Cadmium atom in the Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide (pdb code 7utw). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide, PDB code: 7utw:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in 7utw

Go back to Cadmium Binding Sites List in 7utw
Cadmium binding site 1 out of 2 in the Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cd401

b:13.8
occ:1.00
NE2 A:HIS67 2.3 12.6 1.0
SG A:CYS174 2.3 12.5 1.0
O9 A:CXF404 2.4 13.2 1.0
SG A:CYS46 2.4 11.3 1.0
C7 A:CXF404 3.1 12.5 1.0
CD2 A:HIS67 3.2 12.7 1.0
CE1 A:HIS67 3.2 12.2 1.0
CB A:CYS46 3.3 10.8 1.0
C5N A:NAI403 3.3 9.4 1.0
CB A:CYS174 3.3 10.9 1.0
C4N A:NAI403 3.9 9.4 1.0
C6N A:NAI403 4.0 10.2 1.0
OG A:SER48 4.0 11.8 1.0
CB A:SER48 4.2 11.3 1.0
NH2 A:ARG369 4.3 12.8 1.0
OE2 A:GLU68 4.3 13.7 1.0
ND1 A:HIS67 4.4 11.4 1.0
N8 A:CXF404 4.4 14.2 1.0
CG A:HIS67 4.4 11.5 1.0
CA A:CYS174 4.7 9.7 1.0
CA A:CYS46 4.8 11.1 1.0
N A:GLY175 4.8 10.5 1.0
C A:CYS174 4.9 10.2 1.0
N A:SER48 5.0 10.3 1.0

Cadmium binding site 2 out of 2 in 7utw

Go back to Cadmium Binding Sites List in 7utw
Cadmium binding site 2 out of 2 in the Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Cd-Substituted Horse Liver Alcohol Dehydrogenase in Complex with Nadh and N-Cyclohexylformamide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cd401

b:16.2
occ:1.00
NE2 B:HIS67 2.3 15.7 1.0
O9 B:CXF404 2.4 15.3 1.0
SG B:CYS174 2.4 15.4 1.0
SG B:CYS46 2.4 13.2 1.0
C7 B:CXF404 3.1 15.5 1.0
CE1 B:HIS67 3.2 14.1 1.0
CD2 B:HIS67 3.3 15.5 1.0
CB B:CYS46 3.3 13.1 1.0
CB B:CYS174 3.3 13.6 1.0
C5N B:NAI403 3.4 12.6 1.0
C6N B:NAI403 4.0 13.3 1.0
C4N B:NAI403 4.0 12.9 1.0
OG B:SER48 4.1 13.8 1.0
CB B:SER48 4.2 13.3 1.0
NH2 B:ARG369 4.2 15.4 1.0
ND1 B:HIS67 4.4 13.9 1.0
OE1 B:GLU68 4.4 16.4 1.0
CG B:HIS67 4.4 14.1 1.0
N8 B:CXF404 4.4 17.1 1.0
CA B:CYS174 4.7 12.6 1.0
CA B:CYS46 4.8 12.9 1.0
N B:GLY175 4.9 12.5 1.0
C B:CYS174 4.9 12.3 1.0
N B:SER48 5.0 12.5 1.0

Reference:

C.Zheng, S.G.Boxer. Structure of Cd-Substituted Horse Liver Alcohol Dehydrogenase at 1.33 Angstroms Resolution To Be Published.
Page generated: Fri Jul 19 20:14:36 2024

Last articles

Zn in 7WTZ
Zn in 7WTX
Zn in 7WTW
Zn in 7WT5
Zn in 7WTU
Zn in 7WTV
Zn in 7WTT
Zn in 7WT4
Zn in 7WT3
Zn in 7WSS
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy