Cadmium in PDB 8dvq: Ca Domain of Vansa Histidine Kinase

All present enzymatic activity of Ca Domain of Vansa Histidine Kinase:
2.7.13.3;

The structure of Ca Domain of Vansa Histidine Kinase, PDB code: 8dvq was solved by P.J.Loll, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.69 / 2.19
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	69.83, 94.4, 29.77, 90, 90, 90
R / Rfree (%)	19 / 23.6

The binding sites of Cadmium atom in the Ca Domain of Vansa Histidine Kinase (pdb code 8dvq). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Ca Domain of Vansa Histidine Kinase, PDB code: 8dvq:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in the Ca Domain of Vansa Histidine Kinase


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Ca Domain of Vansa Histidine Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd401 b:55.0 occ:1.00 OD1 A:ASP231 2.3 54.8 1.0 NE2 A:HIS229 2.4 49.7 1.0 OD2 A:ASP231 2.4 55.5 1.0 CG A:ASP231 2.7 53.0 1.0 CE1 A:HIS229 3.2 45.7 1.0 CD2 A:HIS229 3.5 47.5 1.0 CB A:ASP231 4.2 54.7 1.0 ND1 A:HIS229 4.4 51.8 1.0 CG A:HIS229 4.5 48.0 1.0 CG2 A:THR263 4.7 48.4 1.0 CA A:ASP231 5.0 55.4 1.0

Cadmium binding site 2 out of 2 in the Ca Domain of Vansa Histidine Kinase


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Ca Domain of Vansa Histidine Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd402 b:52.3 occ:1.00 ND1 A:HIS257 2.3 43.3 1.0 O A:HOH517 2.5 45.4 1.0 CE1 A:HIS257 3.1 41.4 1.0 CG A:HIS257 3.3 40.6 1.0 CB A:HIS257 3.7 38.6 1.0 CA A:HIS257 4.3 46.1 1.0 NE2 A:HIS257 4.3 43.4 1.0 CD2 A:HIS257 4.4 39.5 1.0 O A:ILE256 4.5 44.5 1.0

K.C.Grasty, C.Guzik, E.J.D'lauro, S.B.Padrick, J.Beld, P.J.Loll. Structure of Vans From Vancomycin-Resistant Enterococci: A Sensor Kinase with Weak Atp Binding. J.Biol.Chem. V. 299 03001 2023.
ISSN: ESSN 1083-351X
PubMed: 36764524
DOI: 10.1016/J.JBC.2023.103001