Cadmium in PDB 8oyl: Coiled-Coil Domain of Human Stil, Q729L Mutant

The structure of Coiled-Coil Domain of Human Stil, Q729L Mutant, PDB code: 8oyl was solved by F.J.O.Martin, M.Shamir, D.N.Woolfson, A.Friedler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.46 / 1.92
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	24.974, 34.942, 72.321, 90, 90, 90
R / Rfree (%)	14.9 / 19

The structure of Coiled-Coil Domain of Human Stil, Q729L Mutant also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Chlorine	(Cl)	3 atoms

The binding sites of Cadmium atom in the Coiled-Coil Domain of Human Stil, Q729L Mutant (pdb code 8oyl). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 2 binding sites of Cadmium where determined in the Coiled-Coil Domain of Human Stil, Q729L Mutant, PDB code: 8oyl:
Jump to Cadmium binding site number: 1; 2;

Cadmium binding site 1 out of 2 in the Coiled-Coil Domain of Human Stil, Q729L Mutant


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Coiled-Coil Domain of Human Stil, Q729L Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd102 b:28.2 occ:0.50 OE2 A:GLU11 2.3 21.0 1.0 OE1 A:GLU11 2.6 21.9 1.0 CD A:GLU11 2.8 20.7 1.0 CL A:CL104 2.8 31.2 1.0 CG A:GLU11 4.3 19.5 1.0 NE A:ARG7 4.4 18.9 1.0 CD A:ARG7 4.6 17.8 1.0 CG A:ARG7 4.7 16.0 1.0

Cadmium binding site 2 out of 2 in the Coiled-Coil Domain of Human Stil, Q729L Mutant


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of Coiled-Coil Domain of Human Stil, Q729L Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd103 b:50.9 occ:1.00 OD1 A:ASP4 2.4 26.7 1.0 CL A:CL106 2.8 59.6 1.0 OD2 A:ASP4 3.0 29.1 1.0 CG A:ASP4 3.1 24.0 1.0 CL A:CL105 3.6 79.6 1.0 NH1 A:ARG7 4.0 19.4 1.0 NH2 A:ARG7 4.5 21.4 1.0 CB A:ASP4 4.6 21.3 1.0 O A:HOH208 4.7 27.8 1.0 CZ A:ARG7 4.7 19.6 1.0 O A:HOH203 4.7 25.9 1.0

M.Shamir, F.J.O.Martin, D.N.Woolfson, A.Friedler. Molecular Mechanism of Stil Coiled-Coil Domain Oligomerization Int J Mol Sci 2023.
ISSN: ESSN 1422-0067
DOI: 10.3390/IJMS241914616