Cadmium in PDB 3lkw: Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant

Enzymatic activity of Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant

All present enzymatic activity of Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant:
2.1.1.56; 2.1.1.57; 2.7.7.48; 3.4.21.91; 3.6.1.15; 3.6.4.13;

Protein crystallography data

The structure of Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant, PDB code: 3lkw was solved by S.Chandramouli, J.S.Joseph, S.Daudenarde, J.Gatchalian, C.Cornillez-Ty, P.Kuhn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	50.00 / 2.00
*Space group*	I 2 2 2
*Cell size a, b, c (Å), α, β, γ (°)*	56.868, 60.893, 160.616, 90.00, 90.00, 90.00
*R / R_free (%)*	20.5 / 24.9

Other elements in 3lkw:

The structure of Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

Cadmium Binding Sites:

The binding sites of Cadmium atom in the Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant (pdb code 3lkw). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total only one binding site of Cadmium was determined in the Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant, PDB code: 3lkw:

Cadmium binding site 1 out of 1 in 3lkw

Go back to

Cadmium Binding Sites List in 3lkw

Cadmium binding site 1 out of 1 in the Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant

Mono view

Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Crystal Structure of Dengue Virus 1 NS2B/NS3 Protease Active Site Mutant within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cd301 b:38.5 occ:1.00	ND1	A:HIS23	1.9	30.6	1.0
	ND1	A:HIS28	2.1	51.2	1.0
	OE2	A:GLU144	2.4	30.8	1.0
	OE1	A:GLU144	2.4	30.9	1.0
	O	A:HOH433	2.5	30.7	1.0
	CE1	A:HIS23	2.7	39.7	1.0
	CD	A:GLU144	2.7	24.3	1.0
	CE1	A:HIS28	2.9	52.4	1.0
	CG	A:HIS23	3.1	36.8	1.0
	CG	A:HIS28	3.3	48.3	1.0
	CB	A:HIS23	3.7	38.9	1.0
	CB	A:HIS28	3.7	43.6	1.0
	NE2	A:HIS23	3.9	33.9	1.0
	NE2	A:HIS28	4.1	53.5	1.0
	CD2	A:HIS23	4.1	34.9	1.0
	CA	A:HIS28	4.1	43.1	1.0
	CG	A:GLU144	4.2	34.1	1.0
	CD2	A:HIS28	4.3	52.3	1.0
	NE2	A:GLN160	4.5	33.1	1.0
	O	A:GLN160	4.7	32.8	1.0
	O	A:HOH419	4.8	47.3	1.0
	CG	A:GLN160	4.8	34.2	1.0
	O	A:HOH418	4.9	46.5	1.0
	O	A:SER27	4.9	49.7	1.0
	N	A:ASN29	4.9	38.8	1.0
	CA	A:HIS23	5.0	41.0	1.0

Reference:

S.Chandramouli, J.S.Joseph, S.Daudenarde, J.Gatchalian, C.Cornillez-Ty, P.Kuhn. Serotype-Specific Structural Differences in the Protease-Cofactor Complexes of the Dengue Virus Family. J.Virol. V. 84 3059 2010.
ISSN: ISSN 0022-538X
PubMed: 20042502
DOI: 10.1128/JVI.02044-09

Page generated: Thu Jul 10 12:46:30 2025

Last articles

Zn in 4IDW
Zn in 4IE0
Zn in 4ICQ
Zn in 4IDR
Zn in 4IC3
Zn in 4IC2
Zn in 4IBZ
Zn in 4IBY
Zn in 4IBW
Zn in 4IBV

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy