Cadmium in PDB 4tz9: Structure of Metallo-Beta-Lactamase

The structure of Structure of Metallo-Beta-Lactamase, PDB code: 4tz9 was solved by J.A.Ferguson, J.Brem, A.Makena, A.M.Mcdonough, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	2.19 / 2.13
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	120.908, 120.908, 90.190, 90.00, 90.00, 90.00
R / Rfree (%)	22.9 / 24.9

The structure of Structure of Metallo-Beta-Lactamase also contains other interesting chemical elements:

Nickel	(Ni)	4 atoms
Cobalt	(Co)	1 atom
Zinc	(Zn)	1 atom

The binding sites of Cadmium atom in the Structure of Metallo-Beta-Lactamase (pdb code 4tz9). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total only one binding site of Cadmium was determined in the Structure of Metallo-Beta-Lactamase, PDB code: 4tz9:

Cadmium binding site 1 out of 1 in the Structure of Metallo-Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Structure of Metallo-Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd304 b:32.5 occ:1.00 NE2 A:HIS250 2.7 33.9 1.0 SG A:CYS208 2.7 28.9 1.0 OD2 A:ASP124 2.7 34.6 1.0 O A:HOH411 2.7 36.8 1.0 O A:HOH490 2.7 16.7 1.0 O A:HOH506 3.5 30.0 1.0 CG A:ASP124 3.5 33.5 1.0 CE1 A:HIS250 3.5 33.4 1.0 CB A:CYS208 3.5 31.2 1.0 CD2 A:HIS250 3.6 36.2 1.0 ZN A:ZN301 3.6 27.1 1.0 OD1 A:ASP124 3.7 29.3 1.0 NE2 A:HIS189 4.2 29.8 1.0 O A:HOH493 4.4 39.9 1.0 CE1 A:HIS189 4.6 30.8 1.0 ND1 A:HIS250 4.6 35.6 1.0 CG A:HIS250 4.6 36.9 1.0 CB A:SER249 4.7 31.1 1.0 CB A:ASP124 4.7 34.7 1.0 CE1 A:HIS120 4.8 25.5 1.0 CA A:CYS208 4.8 30.2 1.0 NE2 A:HIS120 4.8 22.9 1.0 OG A:SER249 5.0 32.0 1.0

J.A.Ferguson, A.Makena, J.Brem, A.M.Mcdonough, C.J.Schofield. Structure of Metallo-Beta-Lactamase To Be Published.