Cadmium in PDB 4tzb: Structure of Ndm-Metallo-Beta-Lactamase

The structure of Structure of Ndm-Metallo-Beta-Lactamase, PDB code: 4tzb was solved by J.A.Ferguson, A.Makena, J.Brem, M.A.Mcdonough, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.05 / 2.03
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	120.244, 120.244, 89.192, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 20.6

The structure of Structure of Ndm-Metallo-Beta-Lactamase also contains other interesting chemical elements:

Nickel	(Ni)	4 atoms
Cobalt	(Co)	1 atom
Zinc	(Zn)	1 atom

The binding sites of Cadmium atom in the Structure of Ndm-Metallo-Beta-Lactamase (pdb code 4tzb). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total only one binding site of Cadmium was determined in the Structure of Ndm-Metallo-Beta-Lactamase, PDB code: 4tzb:

Cadmium binding site 1 out of 1 in the Structure of Ndm-Metallo-Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of Structure of Ndm-Metallo-Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd304 b:31.8 occ:1.00 NE2 A:HIS250 2.6 33.0 1.0 OD2 A:ASP124 2.7 33.1 1.0 SG A:CYS208 2.7 31.6 1.0 O A:HOH521 2.7 24.8 1.0 O A:HOH416 2.8 32.2 1.0 O A:HOH537 3.1 52.9 1.0 O A:HOH504 3.4 52.0 1.0 CB A:CYS208 3.5 29.6 1.0 CG A:ASP124 3.5 32.0 1.0 CD2 A:HIS250 3.5 33.7 1.0 ZN A:ZN301 3.6 29.6 1.0 CE1 A:HIS250 3.6 32.8 1.0 OD1 A:ASP124 3.7 31.5 1.0 NE2 A:HIS189 4.1 28.5 1.0 CE1 A:HIS189 4.3 27.8 1.0 CB A:SER249 4.6 33.3 1.0 CA A:CYS208 4.7 29.9 1.0 ND1 A:HIS250 4.7 33.5 1.0 CG A:HIS250 4.7 34.3 1.0 NE2 A:HIS120 4.8 26.7 1.0 CE1 A:HIS120 4.8 27.0 1.0 OG A:SER249 4.8 34.6 1.0 CB A:ASP124 4.8 29.8 1.0

J.A.Ferguson, A.Makena, J.Brem, M.A.Mcdonough, C.J.Schofield. Structure of Metallo-Beta-Lactamase To Be Published.