Cadmium in PDB 6w7e: K2P2.1 (Trek-1), 30 Mm K+

The structure of K2P2.1 (Trek-1), 30 Mm K+, PDB code: 6w7e was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.94 / 3.29
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.368, 122.534, 126.552, 90, 90, 90
R / Rfree (%)	28.8 / 30.7

The structure of K2P2.1 (Trek-1), 30 Mm K+ also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Cadmium atom in the K2P2.1 (Trek-1), 30 Mm K+ (pdb code 6w7e). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 4 binding sites of Cadmium where determined in the K2P2.1 (Trek-1), 30 Mm K+, PDB code: 6w7e:
Jump to Cadmium binding site number: 1; 2; 3; 4;

Cadmium binding site 1 out of 4 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd401 b:237.8 occ:1.00 NE2 A:HIS313 2.7 239.0 1.0 CE1 A:HIS313 3.4 240.4 1.0 CD A:GLU309 3.8 287.6 1.0 CD2 A:HIS313 3.8 239.9 1.0 OE1 A:GLU309 3.9 285.6 1.0 OE2 A:GLU309 4.0 300.0 1.0 CG A:GLU309 4.1 249.4 1.0 CB A:GLU309 4.4 218.4 1.0 ND1 A:HIS313 4.5 242.7 1.0 CG A:HIS313 4.8 238.8 1.0

Cadmium binding site 2 out of 4 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd402 b:295.9 occ:0.50 OH2 A:1PE403 4.1 276.0 1.0

Cadmium binding site 3 out of 4 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Cd401 b:300.0 occ:0.50 NE2 B:HIS313 2.8 223.0 1.0 CE1 B:HIS313 3.3 227.1 1.0 CD2 B:HIS313 3.9 220.8 1.0 ND1 B:HIS313 4.6 228.2 1.0 CG B:HIS313 4.9 225.5 1.0

Cadmium binding site 4 out of 4 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 4 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Cd402 b:300.0 occ:0.50 CE1 B:HIS126 2.9 245.6 1.0 N B:ILE114 2.9 293.4 1.0 O B:ILE114 3.0 297.7 1.0 CD1 B:ILE115 3.1 300.0 1.0 C B:ILE114 3.1 297.7 1.0 C B:GLY113 3.3 296.6 1.0 CA B:ILE114 3.4 300.0 1.0 NE2 B:HIS126 3.6 253.9 1.0 CG1 B:ILE115 3.7 300.0 1.0 O B:GLY113 3.8 300.0 1.0 N B:ILE115 3.8 300.0 1.0 CA B:GLY113 3.9 287.0 1.0 ND1 B:HIS126 4.0 232.9 1.0 CA B:ILE115 4.7 300.0 1.0 CB B:ILE115 4.8 300.0 1.0 NH2 A:ARG77 4.9 245.9 1.0 CD2 B:HIS126 4.9 247.6 1.0 CB B:ILE114 4.9 295.5 1.0

M.Lolicato, A.M.Natale, F.Abderemane-Ali, D.Crottes, S.Capponi, R.Duman, A.Wagner, J.M.Rosenberg, M.Grabe, D.L.Minor Jr.. K 2P Channel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33127683
DOI: 10.1126/SCIADV.ABC9174