Cadmium in PDB 6w84: K2P2.1 (Trek-1), 200 Mm K+

The structure of K2P2.1 (Trek-1), 200 Mm K+, PDB code: 6w84 was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.99 / 3.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	70.627, 121.287, 130.034, 90, 90, 90
R / Rfree (%)	26.3 / 33.4

The structure of K2P2.1 (Trek-1), 200 Mm K+ also contains other interesting chemical elements:

Potassium

(K)

5 atoms

The binding sites of Cadmium atom in the K2P2.1 (Trek-1), 200 Mm K+ (pdb code 6w84). This binding sites where shown within 5.0 Angstroms radius around Cadmium atom.
In total 3 binding sites of Cadmium where determined in the K2P2.1 (Trek-1), 200 Mm K+, PDB code: 6w84:
Jump to Cadmium binding site number: 1; 2; 3;

Cadmium binding site 1 out of 3 in the K2P2.1 (Trek-1), 200 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 1 of K2P2.1 (Trek-1), 200 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd401 b:294.2 occ:1.00 OE2 A:GLU309 2.9 270.8 1.0 NE2 A:HIS313 3.1 298.2 1.0 CE1 A:HIS313 3.2 289.3 1.0 CG A:GLU309 3.7 280.6 1.0 CD A:GLU309 3.7 272.3 1.0 CD2 A:HIS313 4.4 284.8 1.0 ND1 A:HIS313 4.5 281.6 1.0 OE1 A:GLU309 4.8 234.4 1.0

Cadmium binding site 2 out of 3 in the K2P2.1 (Trek-1), 200 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 2 of K2P2.1 (Trek-1), 200 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Cd402 b:295.7 occ:0.50 NE2 A:HIS126 3.4 277.5 1.0 CE1 A:HIS126 3.5 283.3 1.0 OD2 A:ASP263 4.1 300.0 1.0 OD1 A:ASP263 4.2 300.0 1.0 CG A:ASP263 4.4 300.0 1.0 CD2 A:HIS126 4.5 274.8 1.0 ND1 A:HIS126 4.6 295.5 1.0

Cadmium binding site 3 out of 3 in the K2P2.1 (Trek-1), 200 Mm K+


Mono view


Stereo pair view

A full contact list of Cadmium with other atoms in the Cd binding site number 3 of K2P2.1 (Trek-1), 200 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Cd401 b:293.5 occ:1.00 OD2 B:ASP263 2.9 278.5 1.0 CE1 B:HIS126 3.1 286.7 1.0 CD1 B:ILE115 3.3 300.0 1.0 NE2 B:HIS126 3.4 295.6 1.0 CG B:ASP263 3.7 284.6 1.0 OD1 B:ASP263 3.9 201.0 1.0 CG1 B:ILE115 4.0 300.0 1.0 ND1 B:HIS126 4.3 266.7 1.0 O B:ILE114 4.4 300.0 1.0 CD2 B:HIS126 4.7 275.8 1.0

M.Lolicato, A.M.Natale, F.Abderemane-Ali, D.Crottes, S.Capponi, R.Duman, A.Wagner, J.M.Rosenberg, M.Grabe, D.L.Minor Jr.. K 2P Channel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33127683
DOI: 10.1126/SCIADV.ABC9174